LDL Cholesterol Is Not the Real Villain
Original title: Il vero cattivo non è il colesterolo LDL
Authors: Massimo Fioranelli and Gianluca Pazzaglia
Year: 2025
Publication language: Italian. The heading above is an English translation of the title, not confirmation of an English edition.
Looking beyond a single laboratory result
Can cardiovascular risk be adequately described by one cholesterol measurement? Fioranelli and Pazzaglia invite readers to examine lipid metabolism in a wider clinical context, paying particular attention to the number and characteristics of circulating lipoprotein particles and to small, dense LDL.
The book discusses apolipoprotein B, triglycerides, insulin resistance and inflammation, alongside advanced diagnostic approaches and individual clinical assessment. Its central concern is how the information contained in a laboratory report can be related to the person being treated.
Prevention in everyday life
Clinical examples introduce questions about nutrition, physical activity, sleep, stress and preventive strategies. The authors argue for an understanding of lipid metabolism that extends beyond a single number.
This profile describes the book’s perspective. It does not establish small, dense LDL testing as a replacement for guideline-based risk assessment or justify stopping prescribed lipid-lowering treatment. For an evidence discussion, read absolute and relative benefits of statins and the guide to cardiovascular risk.